Webina: an open-source library and web app that runs AutoDock Vina entirely in the web browser

Bioinformatics. 2020 Aug 15;36(16):4513-4515. doi: 10.1093/bioinformatics/btaa579.


Motivation: Molecular docking is a computational technique for predicting how a small molecule might bind a macromolecular target. Among docking programs, AutoDock Vina is particularly popular. Like many docking programs, Vina requires users to download/install an executable file and to run that file from a command-line interface. Choosing proper configuration parameters and analyzing Vina output is also sometimes challenging. These issues are particularly problematic for students and novice researchers.

Results: We created Webina, a new version of Vina, to address these challenges. Webina runs Vina entirely in a web browser, so users need only visit a Webina-enabled webpage. The docking calculations take place on the user's own computer rather than a remote server.

Availability and implementation: A working version of the open-source Webina app can be accessed free of charge from http://durrantlab.com/webina.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Computers*
  • Humans
  • Ligands
  • Molecular Docking Simulation
  • Software*
  • Web Browser


  • Ligands