Nosocomial Transmission of Coronavirus Disease 2019: A Retrospective Study of 66 Hospital-acquired Cases in a London Teaching Hospital

Clin Infect Dis. 2021 Feb 16;72(4):690-693. doi: 10.1093/cid/ciaa816.


Coronavirus disease 2019 (COVID-19) can cause deadly healthcare-associated outbreaks. In a major London teaching hospital, 66 of 435 (15%) COVID-19 inpatient cases between 2 March and 12 April 2020 were definitely or probably hospital-acquired, through varied transmission routes. The case fatality was 36%. Nosocomial infection rates fell following comprehensive infection prevention and control measures.

Keywords: COVID-19; healthcare-associated infection; infection prevention and control; nosocomial; transmission.

MeSH terms

  • COVID-19*
  • Cross Infection* / epidemiology
  • Disease Outbreaks
  • Hospitals, Teaching
  • Humans
  • London / epidemiology
  • Retrospective Studies
  • SARS-CoV-2