Preparation and activities of selenium polysaccharide from plant such as Grifola frondosa

Carbohydr Polym. 2020 Aug 15:242:116409. doi: 10.1016/j.carbpol.2020.116409. Epub 2020 May 12.

Abstract

Selenium polysaccharide is an organic selenium compound formed by the combination of polysaccharide and selenium. The biological activity of selenium polysaccharide from plant such as Grifola frondosa is generally higher than that of selenium and polysaccharide, and it is more easily absorbed and utilized by human body. Therefore, selenium polysaccharide has a wide range of applications in immune regulation, anti-tumor, anti-oxidation, anti-aging and so on. Due to the unique pharmacological activity of selenium polysaccharide, the research of selenium polysaccharide has gradually become a hot spot. At present, there are few kinds of selenium polysaccharide, but its structure is very complex. The chemical structure and mechanism of selenium polysaccharide in vivo are not completely clear and need further study. Herein, the preparation and biological activities of selenium polysaccharides were introduced systematically, which provided theoretical basis for further research and application of selenium polysaccharides.

Keywords: Activities; Plant polysaccharide; Polysaccharide selenide; Preparation.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Cytokines / metabolism
  • Grifola / chemistry*
  • Humans
  • Immunologic Factors / chemistry
  • Immunologic Factors / isolation & purification
  • Immunologic Factors / pharmacology*
  • Molecular Structure
  • Neoplasms / drug therapy*
  • Organoselenium Compounds / chemistry
  • Organoselenium Compounds / isolation & purification
  • Organoselenium Compounds / pharmacology*
  • Polysaccharides / chemistry
  • Polysaccharides / isolation & purification
  • Polysaccharides / pharmacology*
  • Reactive Oxygen Species / antagonists & inhibitors
  • Reactive Oxygen Species / metabolism

Substances

  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • Cytokines
  • Immunologic Factors
  • Organoselenium Compounds
  • Polysaccharides
  • Reactive Oxygen Species