Can artificial intelligence identify effective COVID-19 therapies?

EMBO Mol Med. 2020 Aug 7;12(8):e12817. doi: 10.15252/emmm.202012817. Epub 2020 Jul 7.

Abstract

In this issue of EMBO Molecular Medicine, Stebbing et al (2020b) validate an artificial intelligence-assisted prediction that a drug used to treat rheumatoid arthritis could be a potent weapon against COVID-19. Using liver organoids infected with SARS-CoV-2, they confirm dual antiviral and anti-inflammatory activities and show that its administration in four COVID-19 patients is correlated with disease improvement, paving the way for more rigorous placebo-controlled trials.

Publication types

  • Comment

MeSH terms

  • Artificial Intelligence
  • Azetidines
  • Betacoronavirus*
  • COVID-19
  • Coronavirus Infections*
  • Humans
  • Pandemics*
  • Pneumonia, Viral*
  • SARS-CoV-2
  • Sulfonamides

Substances

  • Azetidines
  • Sulfonamides
  • baricitinib