Localisation, Personalisation and Delivery of Best Practice Guidelines on an Integrated Care and Cure Cloud Architecture: The C3-Cloud Approach to Managing Multimorbidity

Stud Health Technol Inform. 2020 Jun 16:270:623-627. doi: 10.3233/SHTI200235.


Background: C3-Cloud is an integrated care ICT infrastructure offering seamless patient-centered approach to managing multimorbidity, deployed in three European pilot sites. Challenge: The digital delivery of best practice guidelines unified for multimorbidity, customized to local practice, offering the capability to improve patient personalization and benefit.

Method: C3-Cloud has adopted a co-production approach to developing unified multimorbidity guidelines, by collating and reconciling best practice guidelines for each condition. Clinical and technical teams at pilot sites and the C3-Cloud consortium worked in tandem to create the specification and technical implementation.

Results: C3-Cloud offers CDSS for diabetes, renal failure, depression and congenital heart failure, with over 300 rules and checks that deliver four best practice guidelines in parallel, customized for each pilot site.

Conclusions: The process provided a traceable, maintainable and audited digitally delivered collated and reconciled guidelines.

Keywords: clinical decision support; clinical interpretable guidelines; co-production; integrated care; multimorbidity.

MeSH terms

  • Delivery of Health Care, Integrated*
  • Humans
  • Multimorbidity*