Linking Genome and Exposome: Computational Analysis of Human Variation in Chemical-Target Interactions

Stud Health Technol Inform. 2020 Jun 16:270:1331-1332. doi: 10.3233/SHTI200427.

Abstract

The growing amount of available public data repositories containing a plethora of rich chemical and biomedical information is enabling new in silico research avenues. In this project we aim to link human genome variations and the exposome applying in silico biomedical informatics approaches to analyse the potential effects of those variants in the interactions with different chemicals.

Keywords: Protein modelling; Translational bioinformatics; exposome; single nucleotide variant; toxicogenomics.

MeSH terms

  • Exposome*
  • Genome, Human*
  • Humans