Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion

Blood. 2020 Aug 6;136(6):755-759. doi: 10.1182/blood.2020007079.

Abstract

Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Betacoronavirus / isolation & purification
  • Betacoronavirus / physiology
  • Blood Component Transfusion / methods
  • COVID-19
  • China / epidemiology
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / therapy*
  • Female
  • Humans
  • Immunization, Passive / methods
  • Male
  • Middle Aged
  • Pandemics
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / therapy*
  • SARS-CoV-2
  • Treatment Outcome
  • Viral Load

Supplementary concepts

  • COVID-19 serotherapy