Combination of pregabalin and transcutaneous electrical nerve stimulation for neuropathic pain in a stroke patient after contralateral C7 nerve transfer: a case report

Int J Neurosci. 2021 Dec;131(12):1248-1253. doi: 10.1080/00207454.2020.1786687. Epub 2020 Jun 26.

Abstract

Background: Contralateral C7 nerve transfer is a new surgical treatment for stroke patients with unilateral upper extremity paralysis, but neuropathic pain in the nonparalyzed side is the common complication after surgery. We report a stroke patient with neuropathic pain after C7 nerve transfer who received combination treatment of transcutaneous electrical nerve stimulation(TENS) and pregabalin.

Case summary: A 53-year old, 6 months post-stroke patient with right hemiplegia after contralateral C7 nerve transfer was admitted in our department with a significant neuropathic pain in his left upper extremity. The treatment of pregabalin and TENS were used for patient. The visual analogue scale(VAS), medical outcomes study sleep scale(MOS-SS) and hospital anxiety and depression scale(HADS) were assessed after 1 months treatment. After treatment, the pain of his nonparalyzed upper extremity was relieved, the sleeping quality and the anxiety and depression were improved in patient.

Conclusion: This report suggests that the combination of pregabalin and TENS have prominent clinical effects on neuropathic pain of nonparalyzed side in stroke patients after contralateral C7 nerve transfer.

Keywords: Contralateral C7 nerve transfer; TENS; neuropathic pain; pregabalin.

Publication types

  • Case Reports

MeSH terms

  • Analgesics / pharmacology*
  • Combined Modality Therapy
  • Humans
  • Middle Aged
  • Nerve Transfer / adverse effects*
  • Neuralgia / etiology
  • Neuralgia / therapy*
  • Paralysis / etiology
  • Paralysis / surgery*
  • Pregabalin / pharmacology*
  • Stroke / complications
  • Stroke / therapy*
  • Transcutaneous Electric Nerve Stimulation*
  • Upper Extremity / surgery*

Substances

  • Analgesics
  • Pregabalin