t(1;19) and t(12;17) in childhood acute lymphoblastic leukemia of pre-B type

F Ghione; D Gargano; C Guazzelli; A Lippi

doi:10.1016/0165-4608(88)90228-2

t(1;19) and t(12;17) in childhood acute lymphoblastic leukemia of pre-B type

Cancer Genet Cytogenet. 1988 Apr;31(2):275-8. doi: 10.1016/0165-4608(88)90228-2.

Authors

F Ghione¹, D Gargano, C Guazzelli, A Lippi

Affiliation

¹ Sezione di Ematologia, Clinica Pediatrica III, Universita degli Studi di Firenze, Firenze, Italy.

PMID: 3258176
DOI: 10.1016/0165-4608(88)90228-2

Abstract

We report on a patient with pre-B acute lymphoblastic leukemia (ALL) and t(t;19) as the principal chromosomal abnormality. The presence of the subsequent t(12;17) and the correlation between the chromosomal anomalies and the immunologic phenotype is discussed.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

B-Lymphocytes
Child, Preschool
Chromosome Banding
Chromosomes, Human, Pair 1*
Chromosomes, Human, Pair 12*
Chromosomes, Human, Pair 17*
Chromosomes, Human, Pair 19*
Humans
Karyotyping
Leukemia, Lymphoid / genetics*
Male
Translocation, Genetic*