Clinical characteristics difference between early and late recurrence of ovarian endometriosis after laparoscopic cystectomy

Arch Gynecol Obstet. 2020 Oct;302(4):905-913. doi: 10.1007/s00404-020-05657-5. Epub 2020 Jun 24.


Background: Ovarian endometriosis is the most frequent type of endometriosis. Despite the use of surgery and medication, many patients suffer from recurrence within near future. Currently, there are no effective clinical characteristics available to predict the time to recurrence in ovarian endometriosis patients.

Purpose: To identify the effective clinical indicators for early and late endometrioma recurrence, we compared the clinical characteristics of early and late recurrence after treatment.

Methods: We collected 358 patients with ovarian endometriosis who had a minimum of 5 years of postoperative follow-up after undergoing a laparoscopic excision of ovarian endometrioma performed at Peking Union Medical College Hospital from January 2009 to April 2013.

Results: A total of 358 patients were recruited in the validation set, with a median follow-up time of 83 months (60-120 months). Till the last follow-up, 68 patients exhibited recurrence. Three-year and 5-year recurrence rates were 9.2% and 15.4%, respectively. Univariate analysis in our study showed that patient with endometrioma surgery history had higher incidence of recurrence in 3 years after re-surgery (OR: 5.594, P = 0.029). Univariate and multivariate analyses using the logistic regression showed that the presence of tenesmus before surgery affected the incidence of early recurrence with a ratio of 57.9% (11/19) and 89.5% (17/19) in 3 years and 5 years after surgery, respectively.

Conclusions: Presence of tenesmus before surgery may be linked to the early recurrence of endometrioma.

Keywords: Early recurrence; Laparoscopic cystectomy; Late recurrence; Ovarian endometriosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cystectomy / methods*
  • Endometriosis / surgery*
  • Female
  • Humans
  • Laparoscopy / methods*
  • Neoplasm Recurrence, Local / surgery*
  • Ovarian Diseases / surgery*
  • Treatment Outcome