Optical theranostics and treatment dosimetry for COVID-19 lung complications: Towards increasing the survival rate of vulnerable populations

Photodiagnosis Photodyn Ther. 2020 Sep:31:101892. doi: 10.1016/j.pdpdt.2020.101892. Epub 2020 Jun 22.

Abstract

  1. The progression of the COVID-19 pandemic was slowed by implemented social isolation measures and adaptation of the healthcare system.

  2. Still, no effective treatments for severe lung complications are available for the most susceptible populations.

  3. Optical theranostics methods can identify COVID-19 pulmonary manifestations and provide automated and real-time control of the treatment dosimetry.

  4. Optical methods are flexible for combination with existing medical devices and drug repurposing protocols.

  5. Implementation of reliable and safe theranostics methods requires strong collaboration among researchers, industry and medical institutions.

Publication types

  • Letter

MeSH terms

  • Anti-Infective Agents / administration & dosage*
  • COVID-19
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / drug therapy*
  • Coronavirus Infections / mortality*
  • Female
  • Humans
  • Male
  • Pandemics / prevention & control
  • Pandemics / statistics & numerical data
  • Photochemotherapy / methods*
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / drug therapy*
  • Pneumonia, Viral / mortality*
  • Quality Improvement
  • Radiometry / methods
  • Severe Acute Respiratory Syndrome / drug therapy*
  • Severe Acute Respiratory Syndrome / mortality
  • Survival Analysis
  • Theranostic Nanomedicine / methods*
  • Treatment Outcome
  • Vulnerable Populations

Substances

  • Anti-Infective Agents