Epidemiology of Follicular Lymphoma

Hematol Oncol Clin North Am. 2020 Aug;34(4):631-646. doi: 10.1016/j.hoc.2020.02.001. Epub 2020 May 5.


Follicular lymphoma (FL) is a common indolent lymphoma subtype in Western countries. FL incidence increases with age, and shows considerable variation by race/ethnicity and geography. In the United States and France, FL incidence has been stable since 2000, whereas in other Western and Asian countries it has been increasing. Five-year relative survival rates have been increasing in Western and Asian countries. Progress on identifying FL-specific risk factors has accelerated with the implementation of the InterLymph nested classification and the availability of larger epidemiologic studies and pooled analyses. Identification of risk factors for FL requires further research.

Keywords: Environmental; Epidemiology; Follicular lymphoma; Genetics; Infection; Prevention; Risk.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Age Distribution
  • Combined Modality Therapy
  • Disease Management
  • Disease Susceptibility
  • Genetic Predisposition to Disease
  • Humans
  • Incidence
  • Lymphoma, Follicular / epidemiology*
  • Lymphoma, Follicular / etiology
  • Lymphoma, Follicular / prevention & control
  • Lymphoma, Follicular / therapy
  • Risk Assessment
  • Risk Factors
  • SEER Program
  • Survival Rate
  • Treatment Outcome
  • United States / epidemiology