A systematic review of the effect of platelet-rich plasma on androgenetic alopecia of women

Dermatol Ther. 2020 Nov;33(6):e13835. doi: 10.1111/dth.13835. Epub 2020 Jul 31.


Androgenetic alopecia (AGA) is the most common disease associated with hair loss in both females and males. Given the high prevalence of AGA and limited therapeutic methods and the high cost of hair transplantation and ease of use or platelet-rich plasma (PRP) therapies, this systematic review study was conducted to evaluate the effect of PRP on AGA of women. In this systematic review study, English-language articles were searched on PubMed, ISI web of knowledge, and Google Scholar by the end of 2019 with a combination of keywords. Finally, six articles were evaluated. The total number of subjects in this systematic review study was 92 people in six studies. All studies were clinical trials. Most of the studied had been conducted as a pilot study. Follow-up period for patients varied from 6 to 12 months. Except for one study, other studies have reported a positive therapeutic effect for PRP. The major limitation of the studies was the pilot nature and small sample size of these studies. According to the limited studies included in this systematic review, PRP treatment had a positive effect on the improvement of AGA, increasing hair density, and improving hair diameter in affected women.

Keywords: androgenetic alopecia; platelet-rich plasma (PRP); women.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Alopecia* / diagnosis
  • Alopecia* / therapy
  • Female
  • Hair
  • Humans
  • Male
  • Pilot Projects
  • Platelet-Rich Plasma*
  • Treatment Outcome