In Adults with Acute Achilles Tendon Rupture, a Single Platelet-Rich Plasma Injection Did Not Improve Muscle-Tendon Function at 24 Weeks

doi:10.2106/JBJS.20.00993

Comment

. 2020 Aug 19;102(16):1466.

doi: 10.2106/JBJS.20.00993.

In Adults with Acute Achilles Tendon Rupture, a Single Platelet-Rich Plasma Injection Did Not Improve Muscle-Tendon Function at 24 Weeks

Pieter D'Hooghe¹, Gustavo Vinagre

Affiliations

PMID: 32590399
DOI: 10.2106/JBJS.20.00993

Comment

In Adults with Acute Achilles Tendon Rupture, a Single Platelet-Rich Plasma Injection Did Not Improve Muscle-Tendon Function at 24 Weeks

Pieter D'Hooghe et al. J Bone Joint Surg Am. 2020.

. 2020 Aug 19;102(16):1466.

doi: 10.2106/JBJS.20.00993.

Authors

Pieter D'Hooghe¹, Gustavo Vinagre

Affiliation

¹ Department of Orthopaedic Surgery, Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar.

PMID: 32590399
DOI: 10.2106/JBJS.20.00993

No abstract available

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Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial.
Keene DJ, Alsousou J, Harrison P, Hulley P, Wagland S, Parsons SR, Thompson JY, O'Connor HM, Schlüssel MM, Dutton SJ, Lamb SE, Willett K; PATH-2 trial group. Keene DJ, et al. BMJ. 2019 Nov 20;367:l6132. doi: 10.1136/bmj.l6132. BMJ. 2019. PMID: 31748208 Free PMC article. Clinical Trial.

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Slowed-Down Rehabilitation Following Percutaneous Repair of Achilles Tendon Rupture.
Maffulli N, Gougoulias N, Maffulli GD, Oliva F, Migliorini F. Maffulli N, et al. Foot Ankle Int. 2022 Feb;43(2):244-252. doi: 10.1177/10711007211038594. Epub 2021 Sep 28. Foot Ankle Int. 2022. PMID: 34581220 Free PMC article.
Reparative and Maladaptive Inflammation in Tendon Healing.
Arvind V, Huang AH. Arvind V, et al. Front Bioeng Biotechnol. 2021 Jul 19;9:719047. doi: 10.3389/fbioe.2021.719047. eCollection 2021. Front Bioeng Biotechnol. 2021. PMID: 34350166 Free PMC article. Review.

References

1. Yan R, Gu Y, Ran J, Hu Y, Zheng Z, Zeng M, Heng BC, Chen X, Yin Z, Chen W, Shen W, Ouyang H. Intratendon delivery of leukocyte-poor platelet-rich plasma improves healing compared with leukocyte-rich platelet-rich plasma in a rabbit Achilles tendinopathy model. Am J Sports Med. 2017 Jul;45(8):1909-20. Epub 2017 Mar 16.
1. Krogh TP, Ellingsen T, Christensen R, Jensen P, Fredberg U. Ultrasound-guided injection therapy of Achilles tendinopathy with platelet-rich plasma or saline: a randomized, blinded, placebo-controlled trial. Am J Sports Med. 2016 Aug;44(8):1990-7. Epub 2016 Jun 2.
1. Boesen AP, Hansen R, Boesen MI, Malliaras P, Langberg H. Effect of high-volume injection, platelet-rich plasma, and sham treatment in chronic midportion Achilles tendinopathy: a randomized double-blinded prospective study. Am J Sports Med. 2017 Jul;45(9):2034-43. Epub 2017 May 22.
1. de Jonge S, de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Tol JL. One-year follow-up of platelet-rich plasma treatment in chronic Achilles tendinopathy: a double-blind randomized placebo-controlled trial. Am J Sports Med. 2011 Aug;39(8):1623-9. Epub 2011 May 21.
1. de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Tol JL. Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA. 2010 Jan 13;303(2):144-9.

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[1] Yan R, Gu Y, Ran J, Hu Y, Zheng Z, Zeng M, Heng BC, Chen X, Yin Z, Chen W, Shen W, Ouyang H. Intratendon delivery of leukocyte-poor platelet-rich plasma improves healing compared with leukocyte-rich platelet-rich plasma in a rabbit Achilles tendinopathy model. Am J Sports Med. 2017 Jul;45(8):1909-20. Epub 2017 Mar 16.

[2] Yan R, Gu Y, Ran J, Hu Y, Zheng Z, Zeng M, Heng BC, Chen X, Yin Z, Chen W, Shen W, Ouyang H. Intratendon delivery of leukocyte-poor platelet-rich plasma improves healing compared with leukocyte-rich platelet-rich plasma in a rabbit Achilles tendinopathy model. Am J Sports Med. 2017 Jul;45(8):1909-20. Epub 2017 Mar 16.

[3] Krogh TP, Ellingsen T, Christensen R, Jensen P, Fredberg U. Ultrasound-guided injection therapy of Achilles tendinopathy with platelet-rich plasma or saline: a randomized, blinded, placebo-controlled trial. Am J Sports Med. 2016 Aug;44(8):1990-7. Epub 2016 Jun 2.

[4] Krogh TP, Ellingsen T, Christensen R, Jensen P, Fredberg U. Ultrasound-guided injection therapy of Achilles tendinopathy with platelet-rich plasma or saline: a randomized, blinded, placebo-controlled trial. Am J Sports Med. 2016 Aug;44(8):1990-7. Epub 2016 Jun 2.

[5] Boesen AP, Hansen R, Boesen MI, Malliaras P, Langberg H. Effect of high-volume injection, platelet-rich plasma, and sham treatment in chronic midportion Achilles tendinopathy: a randomized double-blinded prospective study. Am J Sports Med. 2017 Jul;45(9):2034-43. Epub 2017 May 22.

[6] Boesen AP, Hansen R, Boesen MI, Malliaras P, Langberg H. Effect of high-volume injection, platelet-rich plasma, and sham treatment in chronic midportion Achilles tendinopathy: a randomized double-blinded prospective study. Am J Sports Med. 2017 Jul;45(9):2034-43. Epub 2017 May 22.

[7] de Jonge S, de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Tol JL. One-year follow-up of platelet-rich plasma treatment in chronic Achilles tendinopathy: a double-blind randomized placebo-controlled trial. Am J Sports Med. 2011 Aug;39(8):1623-9. Epub 2011 May 21.

[8] de Jonge S, de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Tol JL. One-year follow-up of platelet-rich plasma treatment in chronic Achilles tendinopathy: a double-blind randomized placebo-controlled trial. Am J Sports Med. 2011 Aug;39(8):1623-9. Epub 2011 May 21.

[9] de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Tol JL. Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA. 2010 Jan 13;303(2):144-9.

[10] de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Verhaar JA, Weinans H, Tol JL. Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA. 2010 Jan 13;303(2):144-9.

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In Adults with Acute Achilles Tendon Rupture, a Single Platelet-Rich Plasma Injection Did Not Improve Muscle-Tendon Function at 24 Weeks

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In Adults with Acute Achilles Tendon Rupture, a Single Platelet-Rich Plasma Injection Did Not Improve Muscle-Tendon Function at 24 Weeks

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