Making Sense of Mismatch Negativity

Abstract

Evoked potentials provide valuable insight into brain processes that are integral to our ability to interact effectively and efficiently in the world. The mismatch negativity (MMN) component of the evoked potential has proven highly informative on the ways in which sensitivity to regularity contributes to perception and cognition. This review offers a compendium of research on MMN with a view to scaffolding an appreciation for its use as a tool to explore the way regularities contribute to predictions about the sensory environment over many timescales. In compiling this work, interest in MMN as an index of sensory encoding and memory are addressed, as well as attention. Perspectives on the possible underlying computational processes are reviewed as well as recent observations that invite consideration of how MMN relates to how we learn, what we learn, and why.

Keywords: MMN; auditory; mismatch negativity; predictive coding; stimulus specific adaptation.