Abstract
The adverse reactions of antihypertensive agents are reviewed, including their clinical implications and suggested methods of preventing, detecting and managing them. The drugs discussed are: (1) diuretics--thiazides, furosemide, ethacrynic acid and spironolactone; (2) sympatholytics--reserpine, methyldopa, guanethidine, propranolol and clonidine; (3) vasodilators--hydralazine, prazosin and minoxidil. It is suggested that cooperative multi-disciplinary efforts should be undertaken to counteract the factors which contribute to improper use of antihypertensive agents.
MeSH terms
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Antihypertensive Agents / adverse effects*
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Benzothiadiazines
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Clonidine / adverse effects
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Diuretics
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Drug Interactions
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Ethacrynic Acid / adverse effects
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Furosemide / adverse effects
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Guanethidine / adverse effects
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Humans
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Hydralazine / adverse effects
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Hypertension / drug therapy
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Methyldopa / adverse effects
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Minoxidil / adverse effects
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Prazosin / adverse effects
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Propranolol / adverse effects
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Reserpine / adverse effects
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Sodium Chloride Symporter Inhibitors / adverse effects
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Spironolactone / adverse effects
Substances
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Antihypertensive Agents
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Benzothiadiazines
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Diuretics
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Sodium Chloride Symporter Inhibitors
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Hydralazine
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Spironolactone
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Methyldopa
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Minoxidil
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Furosemide
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Reserpine
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Propranolol
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Ethacrynic Acid
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Clonidine
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Prazosin
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Guanethidine