TRANS-FRONTAL SINUS APPROACH FOR OLFACTORY GROOVE MENINGIOMAS: A 19 YEAR EXPERIENCE

Clin Neurol Neurosurg. 2020 Sep:196:106041. doi: 10.1016/j.clineuro.2020.106041. Epub 2020 Jun 24.

Abstract

Introduction: Olfactory groove meningiomas (OGMs) account for 8-13 % of all intracranial meningiomas. The gold standard of treatment is generally surgery, however various approaches have been used and the literature is still uncertain about the superiority of one treatment over the others. The most debated techniques are traditional microscopic open approaches versus the endoscopic endonasal ones. The aim of this paper is to prove a valid surgical route that gathers the benefits of both endoscopic and transcranial routes.

Methods: Fifty consecutive patients underwent trans-frontal sinus surgical removal of an OGM between January 2000 and January 2019 at the Neurosurgical Departments in Torino, Brescia and Legnano (Italy). The clinical features were collected in a database and compared with neuroimaging and outcomes. All patients were investigated with neuroimaging techniques. Clinical evaluations were performed 3-4 months and 1 year after surgery, together with neuroradiological follow-up.

Results: All patients with OGM underwent Simpson grade I resection. The most common neurological symptom leading to neuroradiological evaluations were headaches (36 %), followed by behavioural changes (30 %), hyposmia/anosmia (12 %), visual impairments (6%) and focal deficits (6%). At 3-4 months follow-up 48 patients underwent a brain MRI (2 patients underwent a brain CT), and a complete resection was confirmed in 45 patients (94 %).

Conclusions: Despite different techniques and studies supported by good evidence, there is no consensus on the best surgical approach for OGMs. The data shown in this article suggests that the trans-frontal sinus approach is a valid alternative to an endoscopic approach and the classical transcranial routes, collecting benefits from both approaches.

Keywords: Anterior cranial fossa; Olfactory groove meningioma; Skull base surgery; Trans frontal sinus approach.

MeSH terms

  • Adult
  • Aged
  • Cranial Fossa, Anterior / pathology
  • Cranial Fossa, Anterior / surgery
  • Female
  • Frontal Sinus / surgery
  • Humans
  • Male
  • Meningeal Neoplasms / surgery*
  • Meningioma / surgery*
  • Middle Aged
  • Neurosurgical Procedures / methods*
  • Skull Base Neoplasms / surgery*