[Idiopathic Inflammatory Myopathies]

Dtsch Med Wochenschr. 2020 Jul;145(13):903-910. doi: 10.1055/a-1018-3008. Epub 2020 Jul 2.
[Article in German]


Myositis is a rare and an extremely heterogeneous autoimmune disease, that causes muscle weakness. Currently, "idiopathic inflammatory myopathies (IIM)" is the preferred umbrella-term used to describe the disease complexity within individuals. IIM include dermatomyositis, polymyositis, inclusion body myositis, autoimmune necrotizing myopathy, overlap myositis and antisynthetase syndrome. Research activity concerning myositis was very intense over the past ten years and led to new diagnostic approach as well as to novel therapeutic strategies. Correct classification is the key for successful management. One single treatment regime for every possible organ involvement in all different forms of IIM is still not existing.

Publication types

  • Review

MeSH terms

  • Autoimmune Diseases / classification
  • Autoimmune Diseases / diagnosis*
  • Autoimmune Diseases / therapy
  • Dermatomyositis / classification
  • Dermatomyositis / diagnosis
  • Dermatomyositis / therapy
  • Diagnosis, Differential
  • Humans
  • Muscle Weakness / classification
  • Muscle Weakness / etiology
  • Muscle Weakness / therapy
  • Myositis / classification
  • Myositis / diagnosis*
  • Myositis / therapy
  • Polymyositis / classification
  • Polymyositis / diagnosis
  • Polymyositis / therapy
  • Prognosis

Supplementary concepts

  • Antisynthetase syndrome