National incidence, prevalence and disability-adjusted life years (DALYs) of common micronutrient deficiencies in Ethiopia from 1990 to 2017: estimates from the global burden of diseases study

Glob Health Action. 2020 Dec 31;13(1):1776507. doi: 10.1080/16549716.2020.1776507.

Abstract

Background: Understanding the national burden and trend of micronutrient deficiencies helps to guide effective intervention strategies under various circumstances. There is, however, a lack of evidence on trends, age- and sex-specific variations in Ethiopia.

Objective: This study aimed to provide evidence on the trends of common micronutrient deficiencies including, dietary iron, iodine, vitamin A and other nutritional deficiencies in Ethiopia, from 1990 to 2017, using findings from the Global Burden of Disease study.

Method: We used estimates from the GBD 2017 study to report the incidence, prevalence and disability-adjusted life years of micronutrient deficiencies in Ethiopia from 1990 to 2017. All estimates, both crude counts, as well as all-age and age-standardized rates per 100,000 population, are accompanied by 95% uncertainty intervals (UIs). We summarized the age- and sex-specific patterns and we compared the burden with the sub-Saharan Africa and global estimate.

Results: From 1990 to 2017, the age-standardized prevalence rate of dietary iron, vitamin A and iodine deficiency decreased by 20.1%, 16.7%, and 91.6%, respectively. However, MNDs still account for a large number of DALYs in the country. In 2017, the all-age total DALYs due to dietary iron deficiency were estimated to be 448.4 thousand [95% UI: 298.9-640.7], accounting for 1.18% of the total DALYs. Similarly, the all-age total DALYs due to vitamin A deficiency were 397.8 thousand [256.1-589.2]. The total DALYs due to iodine deficiency were estimated to be 89.6 thousand [48.3-155.4].

Conclusions: Micronutrient deficiencies and associated morbidity and mortality are still high in Ethiopia compared with the sub-Saharan and global estimate. Adolescent and early adult females and children aged under-five are disproportionately affected segments of the population. Therefore, in collaboration with other sectors, the National Nutrition Program needs to place greater emphasis upon improving accessibility and utilization of nutrient-rich foods and supplementation, particularly for vulnerable groups of the population.

Keywords: DALY; Ethiopia; Incidence; iodine; iron; micronutrient deficiency; prevalence; vitamin A.

MeSH terms

  • Adolescent
  • Adult
  • Africa, Northern
  • Child
  • Cost of Illness*
  • Disabled Persons
  • Ethiopia / epidemiology
  • Female
  • Humans
  • Incidence
  • Iron
  • Male
  • Malnutrition* / complications
  • Malnutrition* / epidemiology
  • Micronutrients
  • Nutritional Status
  • Prevalence
  • Quality-Adjusted Life Years*
  • Vitamin A
  • Vitamin A Deficiency

Substances

  • Micronutrients
  • Vitamin A
  • Iron