Management of fetal ductus arteriosus constriction with Digoxin and oxygen therapy

Cardiol Young. 2020 Aug;30(8):1183-1185. doi: 10.1017/S1047951120001560. Epub 2020 Jul 3.

Abstract

Constriction of the fetal ductus arteriosus is rare and usually attributed to medications or CHD. We describe a 24-year-old multigravida at 33 weeks 5 days gestation with echocardiographic findings of severe ductal constriction, a dilated, hypertrophied and hypocontractile right ventricle, and severe tricuspid regurgitation following BC powder® use. Treatment with Digoxin and oxygen resulted in a progressive 71% reduction in peak systolic ductal gradient, improved right ventricular function, and decreased tricuspid regurgitation.

Keywords: Constricted ductus arteriosus; Digoxin; antenatal; oxygen.

MeSH terms

  • Constriction
  • Digoxin
  • Ductus Arteriosus* / diagnostic imaging
  • Female
  • Humans
  • Oxygen
  • Ultrasonography, Prenatal
  • Young Adult

Substances

  • Digoxin
  • Oxygen