Efficacy and safety results of micellar water, cream and serum for rosacea in comparison to a control group

J Cosmet Dermatol. 2020 Oct;19(10):2627-2633. doi: 10.1111/jocd.13591. Epub 2020 Jul 21.

Abstract

Background: Rosacea is a common inflammatory skin disorder with centrofacial erythema, flushing, telangiectasia, papules/pustules, and possible ocular or phymatous manifestation. Patients' skin is particularly sensitive to chemical and physical stimuli leading to burning, stinging, dryness, and skin tightness.

Objective: Dermatological evaluation of the efficacy and safety of skin care products designed for centrofacial erythema in rosacea patients, in comparison with a control group using objective measurements. Rosacea symptoms (itching, tension, warmth, burning, dryness) and quality of life were examined.

Methods: Sixty Caucasians with centrofacial erythema were enrolled in an 8-week prospective study, fifty of them exclusively using the study products (micellar water, cream, and serum) with ten participants randomly assigned to a control group. Patients were evaluated at baseline (V0), at 4 weeks (V1), and at 8 weeks (V2). Three-dimensional objective measurements (VECTRA® ) as well as standardized questionnaires were used.

Results: Results were compared with the control group. A significant reduction of 16% in skin redness as indicated by VECTRA® analysis was seen in the intervention group comparing V0-V2. Furthermore, rosacea-associated symptoms diminished by 57.1%, while life quality of affected patients within the intervention group improved by 54.5% comparing V0-V2, respectively.

Conclusions: A skin care regime suitable for sensitive and redness-prone skin led to an enhanced clinical appearance, to a decrease of associated symptoms in rosacea patients, and to an improved life quality.

Keywords: cosmeceutical; cosmetic dermatology; facial redness; rosacea; skin care.

MeSH terms

  • Control Groups
  • Humans
  • Micelles
  • Prospective Studies
  • Quality of Life*
  • Rosacea* / drug therapy
  • Water

Substances

  • Micelles
  • Water

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