Seroprevalence of SARS-CoV-2 Among Frontline Healthcare Personnel During the First Month of Caring for Patients With COVID-19-Nashville, Tennessee

doi:10.1093/cid/ciaa936

. 2021 May 4;72(9):1645-1648.

doi: 10.1093/cid/ciaa936.

Seroprevalence of SARS-CoV-2 Among Frontline Healthcare Personnel During the First Month of Caring for Patients With COVID-19-Nashville, Tennessee

William B Stubblefield¹, H Keipp Talbot^{2

3}, Leora R Feldstein⁴, Mark W Tenforde⁴, Mohammed Ata Ur Rasheed⁴, Lisa Mills⁴, Sandra N Lester⁴, Brandi Freeman⁴, Natalie J Thornburg⁴, Ian D Jones¹, Michael J Ward¹, Christopher J Lindsell⁵, Adrienne Baughman¹, Natasha Halasa⁶, Carlos G Grijalva³, Todd W Rice², Manish M Patel⁴, Wesley H Self¹

Affiliations

¹ Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
² Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
³ Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
⁴ CDC COVID-19 Response Team, Atlanta, Georgia, USA.
⁵ Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
⁶ Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

PMID: 32628750
PMCID: PMC7454447
DOI: 10.1093/cid/ciaa936

Seroprevalence of SARS-CoV-2 Among Frontline Healthcare Personnel During the First Month of Caring for Patients With COVID-19-Nashville, Tennessee

William B Stubblefield et al. Clin Infect Dis. 2021.

. 2021 May 4;72(9):1645-1648.

doi: 10.1093/cid/ciaa936.

Authors

Affiliations

¹ Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
² Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
³ Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
⁴ CDC COVID-19 Response Team, Atlanta, Georgia, USA.
⁵ Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
⁶ Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

PMID: 32628750
PMCID: PMC7454447
DOI: 10.1093/cid/ciaa936

Abstract

Among 249 healthcare personnel who worked in hospital units with COVID-19 patients for 1 month, 19 (7.6%) tested positive for SARS-CoV-2 antibodies. Only 11 (57.9%) of the 19 personnel with positive serology reported symptoms of a prior illness, suggesting asymptomatic healthcare personnel could be an important source of SARS-CoV-2 transmission.

Keywords: COVID-19; SARS-CoV-2; coronavirus; healthcare personnel; serology.

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References

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[1] Ran L, Chen X, Wang Y, Wu W, Zhang L, Tan X. Risk factors of healthcare workers with corona virus disease 2019: a retrospective cohort study in a designated hospital of Wuhan in China. Clin Infect Dis 2020; 71:2218–221. - PMC - PubMed

[2] Ran L, Chen X, Wang Y, Wu W, Zhang L, Tan X. Risk factors of healthcare workers with corona virus disease 2019: a retrospective cohort study in a designated hospital of Wuhan in China. Clin Infect Dis 2020; 71:2218–221. - PMC - PubMed

[3] Chou R, Dana T, Buckley DI, Selph S, Fu R, Totten AM. Epidemiology of and risk factors for coronavirus infection in health care workers. Ann Intern Med 2020. May 5; M20-1632. doi: 10.7326/M20-1632. Online ahead of print. - DOI - PubMed

[4] Chou R, Dana T, Buckley DI, Selph S, Fu R, Totten AM. Epidemiology of and risk factors for coronavirus infection in health care workers. Ann Intern Med 2020. May 5; M20-1632. doi: 10.7326/M20-1632. Online ahead of print. - DOI - PubMed

[5] US Department of Homeland Security. Advisory memorandum on identification of essential critical infrastructure workers during COVID-19 response. Available at: https://www.cisa.gov/sites/default/files/publications/CISA_Guidance_on_t.... Accessed 6 May 2020.

[6] US Department of Homeland Security. Advisory memorandum on identification of essential critical infrastructure workers during COVID-19 response. Available at: https://www.cisa.gov/sites/default/files/publications/CISA_Guidance_on_t.... Accessed 6 May 2020.

[7] CDC COVID-19 Response Team. Characteristics of health care personnel with COVID-19—United States, February 12-April 9, 2020. MMWR Morb Mortal Wkly Rep 2020; 69:477–81. - PMC - PubMed

[8] CDC COVID-19 Response Team. Characteristics of health care personnel with COVID-19—United States, February 12-April 9, 2020. MMWR Morb Mortal Wkly Rep 2020; 69:477–81. - PMC - PubMed

[9] Zhao J, Yuan Q, Wang H, et al. . Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis 2020; 71:2027–34. - PMC - PubMed

[10] Zhao J, Yuan Q, Wang H, et al. . Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis 2020; 71:2027–34. - PMC - PubMed

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Seroprevalence of SARS-CoV-2 Among Frontline Healthcare Personnel During the First Month of Caring for Patients With COVID-19-Nashville, Tennessee

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Seroprevalence of SARS-CoV-2 Among Frontline Healthcare Personnel During the First Month of Caring for Patients With COVID-19-Nashville, Tennessee

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