Multiple Dimensions and Correlates of Fatigue in Individuals on Hemodialysis

Nephrol Nurs J. 2020 May-Jun;47(3):215-251.

Abstract

This study examined the severity, pattern, and correlates of fatigue among adults undergoing hemodialysis. Measures included the Piper Fatigue Scale (PFS-12), Patient-Reported Outcomes Measurement Information System (PROMIS) - Fatigue, Charlson Comorbidity Index, and Six-Minute Walk Test (6MWT). Patients were excluded if mobility or cardiovascular issues prevented conducting the 6MWT. Participants were 86 cognitively intact adults (M = 61.7 years, SD = 13.81), predominantly male (58.1%), and African American (48.8%), with 80% reporting fatigue in the week prior to hemodialysis. Significant increases were noted in sensory and cognitive fatigue from pre- to post-dialysis, while the 6MWT distance decreased significantly pre- to post-dialysis. Factors significantly associated with pre-dialysis fatigue included low hemoglobin, younger age, and living with someone else, while comorbidities and dialysis inadequacy were trending to significant associations with fatigue.

Keywords: correlate; fatigue; hemodialysis; multidimensional; symptom.

MeSH terms

  • Aged
  • Fatigue / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Renal Dialysis*
  • Risk Factors