Coronavirus Disease among Persons with Sickle Cell Disease, United States, March 20-May 21, 2020

Emerg Infect Dis. 2020 Oct;26(10):2473-2476. doi: 10.3201/eid2610.202792. Epub 2020 Jul 8.

Abstract

Sickle cell disease (SCD) disproportionately affects Black or African American persons in the United States and can cause multisystem organ damage and reduced lifespan. Among 178 persons with SCD in the United States who were reported to an SCD-coronavirus disease case registry, 122 (69%) were hospitalized and 13 (7%) died.

Keywords: COVID-19; SARS-CoV-2; SCD; United States; coronavirus; coronavirus disease; hemoglobin; respiratory diseases; severe acute respiratory syndrome coronavirus 2; sickle cell disease; viruses; zoonoses.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anemia, Sickle Cell / epidemiology*
  • Asymptomatic Infections / epidemiology
  • Betacoronavirus
  • Child
  • Child, Preschool
  • Comorbidity
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / mortality
  • Female
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Pandemics
  • Patient Acuity
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / mortality
  • Registries
  • United States / epidemiology
  • Young Adult

Supplementary concepts

  • COVID-19
  • severe acute respiratory syndrome coronavirus 2