Increased fronto-temporal connectivity by modified melody in real music

PLoS One. 2020 Jul 8;15(7):e0235770. doi: 10.1371/journal.pone.0235770. eCollection 2020.

Abstract

In real music, the original melody may appear intact, with little elaboration only, or significantly modified. Since a melody is most easily perceived in music, hearing significantly modified melody may change a brain connectivity. Mozart KV 265 is comprised of a theme with an original melody of "Twinkle Twinkle Little Star" and its significant variations. We studied whether effective connectivity changes with significantly modified melody, between bilateral inferior frontal gyri (IFGs) and Heschl's gyri (HGs) using magnetoencephalography (MEG). Among the 12 connectivities, the connectivity from the left IFG to the right HG was consistently increased with significantly modified melody compared to the original melody in 2 separate sets of the same rhythmic pattern with different melody (p = 0.005 and 0.034, Bonferroni corrected). Our findings show that the modification of an original melody in a real music changes the brain connectivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Auditory Cortex / physiology*
  • Auditory Perception*
  • Brain / physiology
  • Connectome*
  • Female
  • Humans
  • Magnetoencephalography
  • Male
  • Music*
  • Nerve Net / physiology
  • Prefrontal Cortex / physiology*
  • Young Adult

Grant support

This research was supported by Seoul National University Research Grant in 2018 and the Brain Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (2016M3C7A1904984). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.