Transition metal dichalcogenides and carbonitrides (TMDs and MXenes) have attracted great attention in electrochemistry due to their tunable electronic structures. Herein, a new compound of Nb2Se2C is designed as a "TMD-MXene"-like material. It exhibits better oxygen evolution reaction performance than most other reported TMDs, MXenes, and commercial electrocatalysts due to the enriched active sites and excellent conductivity.