Pediatric Uveitis and Scleritis in a Multi-Ethnic Asian Population

Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1304-1311. doi: 10.1080/09273948.2020.1766083. Epub 2020 Jul 9.

Abstract

Purpose: To describe the demographics and clinical characteristics of pediatric uveitis and scleritis at a tertiary eye care center.Methods: Clinical records of children with either uveitis or scleritis that presented between January 1989 and January 2016 were reviewed retrospectively.Results: Seventy-three patients were identified. Fifty-four had uveitis and 19 had scleritis. Posterior uveitis was the most common (27.8%), followed by intermediate uveitis (25.9%), panuveitis (25.9%) and anterior uveitis. Majority were noninfectious uveitis (37.0%), and 29.6% were idiopathic. Common associations were sarcoidosis (14.8%), HLA-B27 haplotype (9.3%) and toxoplasmosis (7.4%). Posterior scleritis was more common (94.7%) than anterior scleritis and majority were idiopathic (68.4%). Delayed patient presentation and presenting visual acuity worse than 0.3 LogMAR were associated with poor visual outcome (p = .03; OR = 0.17; 95% CI, 0.03-0.84 and p = .007; OR = 0.09; 95% CI, 0.02-0.52 respectively).Conclusion: Majority had noninfectious etiologies. Uveitis associated with juvenile idiopathic arthritis was rare.

Keywords: Prevalence; epidemiology; pediatric; scleritis; uveitis.

MeSH terms

  • Adolescent
  • Asian People / ethnology*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Prevalence
  • Retrospective Studies
  • Scleritis / ethnology*
  • Singapore / epidemiology
  • Tertiary Care Centers
  • Uveitis / classification
  • Uveitis / ethnology*