Astrocytomas represent a significant and complex subset of brain tumors originating from astrocytes, the star-shaped glial cells that play a critical role in supporting neuronal function within the cerebrum. Amongst brain tumors, glial tumors comprise 60% of the tumors. As the most common form of glioma, astrocytomas primarily affect the brain, although they can also involve the spinal cord. These tumors present a considerable clinical challenge due to their prevalence and the serious morbidity and mortality they cause across all age groups. The etiology of astrocytomas remains largely elusive, with ionizing radiation being the only well-established risk factor. Associations with other potential risk factors, such as electromagnetic fields, head injury, or occupational exposures, are not yet supported by conclusive evidence.
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