Drusen Bodies

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.


Drusen bodies are extracellular deposits of lipids, proteins, and cellular debris which are found within the layers of the retina and appear as small, yellow deposits on dilated eye exams. Specifically, drusen reside between the basal lamina of the retinal pigment epithelium (RPE) and the inner layer of the Bruch membrane (BM). These sub-RPE deposits are seen with the progression of normal aging; however, depending on the size, number, location, and type of drusen involved, they can be associated with increased risk of developing age-related macular degeneration (AMD).

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