In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan.


Neurotmesis is a complete transection of a peripheral nerve. The severity of peripheral nerve injury can be classified as neurapraxia, axonotmesis, or neurotmesis according to 1942 Seddon’s classification, or the five different degrees according to the 1951 Sunderland’s classification. Neurotmesis will produce complete sensory and motor deficits to the skin and muscles innervated by the injured nerve. Spontaneous recovery of function is extremely suboptimal without surgical intervention.

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