Dietary Strategies for Maintenance of Clinical Remission in Inflammatory Bowel Diseases: Are We There Yet?

Nutrients. 2020 Jul 7;12(7):2018. doi: 10.3390/nu12072018.


The etiopathogenesis of Inflammatory bowel disease (IBD) is a result of a complex interaction between host immune response, the gut microbiome and environmental factors, such as diet. Although scientific advances, with the use of biological medications, have revolutionized IBD treatment, the challenge for maintaining clinical remission and delaying clinical relapse is still present. As exclusive enteral nutrition has become a well-established treatment for the induction of remission in pediatric Crohn's disease, the scientific interest regarding diet in IBD is now focused on the development of follow-on dietary strategies, which aim to suppress colonic inflammation and delay a disease flare. The objective of this review is to present an extensive overview of the dietary strategies, which have been used in the literature to maintain clinical remission in both Crohn's disease and Ulcerative colitis, and the evidence surrounding the association of dietary components with clinical relapse. We also aim to provide study-related recommendations to be encompassed in future research studies aiming to investigate the role of diet during remission periods in IBD.

Keywords: Crohn’s disease; Ulcerative colitis; clinical relapse; dietary therapy; dietary triggers; inflammatory bowel disease; maintenance enteral nutrition.

Publication types

  • Review

MeSH terms

  • Adult
  • Child
  • Colitis, Ulcerative / diet therapy*
  • Crohn Disease / diet therapy*
  • Diet / methods
  • Enteral Nutrition / methods
  • Gastrointestinal Microbiome
  • Humans
  • Inflammatory Bowel Diseases / diet therapy
  • Recurrence
  • Remission Induction

Supplementary concepts

  • Pediatric Crohn's disease