Abstract
Development of vaccines to highly variable viruses such as Human Immunodeficiency Virus and influenza A viruses faces multiple challenges. In this article, these challenges are described and reverse vaccinology approaches to generate universal vaccines against both pathogens are laid out and compared.
MeSH terms
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AIDS Vaccines / chemistry
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AIDS Vaccines / immunology*
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Antibodies, Viral / immunology*
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Broadly Neutralizing Antibodies / immunology*
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HIV / chemistry
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HIV / immunology*
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Humans
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Influenza Vaccines / chemistry
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Influenza Vaccines / immunology*
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Orthomyxoviridae / chemistry
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Orthomyxoviridae / immunology*
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Vaccinology*
Substances
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AIDS Vaccines
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Antibodies, Viral
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Broadly Neutralizing Antibodies
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Influenza Vaccines