Ophthalmic Complications in Pediatric Uveitis

Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1375-1380. doi: 10.1080/09273948.2020.1762897. Epub 2020 Jul 10.

Abstract

Purpose: We aim to look at the complications encountered by a cohort of pediatric uveitis patients from north India.Methods: Retrospectively, complications seen in patients younger than 16 years diagnosed with uveitis between January 2006 to March 2015 were noted.Results: Data of 104 children, with a mean follow-up of 3.40 ± 2.34 years was studied. Cataract (n = 42, 24.00%), band-shaped keratopathy (n = 32, 18.29%) and Glaucoma/OHT (n = 11, 6.29%) were most encountered complications at presentation. Glaucoma/OHT (29.71%; n = 52), cataract (18.86%; n = 33) and maculopathy (n=12;6.86%) were the most common complications at follow up. Maculopathy (35%) and Glaucoma/OHT (20%) were the most common causes of visual acuity ≤3/60.Conclusions: Cataract is the most critical complication in children with uveitis at presentation and raised intraocular pressure occurs at follow-up, perhaps attributed to the treatment. Maculopathy is the most common cause of blindness in these children.

Keywords: Pediatric; complications; inflammation; ocular; uveitis.

MeSH terms

  • Adolescent
  • Cataract / diagnosis
  • Cataract / etiology*
  • Child
  • Child, Preschool
  • Coloring Agents / administration & dosage
  • Corneal Dystrophies, Hereditary / diagnosis
  • Corneal Dystrophies, Hereditary / drug therapy
  • Corneal Dystrophies, Hereditary / etiology*
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Glaucoma / diagnosis
  • Glaucoma / drug therapy
  • Glaucoma / etiology*
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • India
  • Indocyanine Green / administration & dosage
  • Infant
  • Intraocular Pressure
  • Male
  • Microscopy, Acoustic
  • Ocular Hypertension / diagnosis
  • Ocular Hypertension / drug therapy
  • Ocular Hypertension / etiology
  • Retrospective Studies
  • Uveitis / complications*
  • Uveitis / diagnosis
  • Uveitis / drug therapy
  • Visual Acuity / physiology
  • Visual Field Tests

Substances

  • Coloring Agents
  • Glucocorticoids
  • Immunosuppressive Agents
  • Indocyanine Green

Supplementary concepts

  • Corneal Dystrophy, Lisch Epithelial