Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing

J Clin Med. 2020 Jul 8;9(7):2161. doi: 10.3390/jcm9072161.


Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types, including adipose-derived stem cells (ASCs) with the potential to differentiate into a number of cell lineages, and thus has significant potential for developing therapies for regenerative medicine. Currently, there is no gold standard treatment for scars and impaired wound healing continues to be a challenge faced by clinicians worldwide. This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue before discussing the properties of ASCs and their promising applications for tissue engineering, scarring, and wound healing.

Keywords: adipose tissue; adipose-derived stem cells; fat grafting; regenerative medicine; stromal vascular fraction; wound healing.

Publication types

  • Review