Prevalence of cardiometabolic risk factors and selected cardiovascular diseases in hypertensive and normotensive participants in the adult Polish population: The WOBASZ II study

Arkadiusz Niklas; Justyna Marcinkowska; Magdalena Kozela; Andrzej Pająk; Tomasz Zdrojewski; Wojciech Drygas; Aleksandra Piwońska; Wojciech Bielecki; Krystyna Kozakiewicz; Andrzej Tykarski

doi:10.1097/MD.0000000000021149

Prevalence of cardiometabolic risk factors and selected cardiovascular diseases in hypertensive and normotensive participants in the adult Polish population: The WOBASZ II study

Medicine (Baltimore). 2020 Jul 10;99(28):e21149. doi: 10.1097/MD.0000000000021149.

Affiliations

¹ Department of Hypertension, Angiology and Internal Disease.
² Department of Computer Science and Statistics, University of Medical Science, Poznan.
³ Department of Epidemiology and Population Studies, Institute of Public Health, Faculty of Health Sciences, Jagiellonian University Medical College.
⁴ Department of Arterial Hypertension and Diabetology, Medical University of Gdansk.
⁵ Department of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, National Institute of Cardiology, Warsaw.
⁶ Department of Social Pathologies, Medical University of Lodz.
⁷ 3rd Department of Cardiology, Medical University of Silesia, Katowice, Poland.

Abstract

Hypertension is one of the most important causes of cardiovascular disease (CVD) incidence and mortality. The aim of the study was to assess the prevalence of metabolic syndrome and its individual components i.e., diabetes, obesity, elevated triglycerides (TG), low HDL (high-density lipoprotein) cholesterol, as well as selected manifestations of CVD i.e., atrial fibrillation (AF), peripheral artery disease (PAD), coronary artery disease (CAD), myocardial infarction (MI), and stroke in persons with and without hypertension in the Polish population.The analysis included participants of Polish multicentre WOBASZ II Study i.e., 6163 persons aged 19 and above. The Mantel Haenszel anlysis and multidimensional logistic regression model were used to assess the relations between the prevalence of metabolic syndrome and its individual components as well as selected manifestations of CVD with hypertension.Compared to normotensives, metabolic syndrome was over 5 times more prevalent in participants with hypertension (OR = 5.35, 95% CI:4.71-6.09). Components of the metabolic syndrome and selected manifestations of CVD were more prevalent in participants with hypertension compared to normotensives. The Mantel-Haenszel odds ratios (95% confidence intervals) were as follows: obesity counted as BMI > 30 kg/m OR = 2.58 (2.26-2.96), raised triglycerides OR = 2.34 (2.07-2.64), reduced HDL-C OR = 1.81 (1.59-2.06), metabolic syndrome OR = 5.35 (4.71-6.09), diabetes OR = 2.54 (1.98-3.26), AF OR = 1.47 (1.09-2.00), PAD OR = 1.51 (1.14-1.99), CAD OR = 1.94 (1.52-2.49), MI OR = 1.89 (1.32-2.70), hospitalization due to HF OR = 2.02 (1.43-2.87), hospitalization due to exacerbation of CAD OR = 2.13 (1.58-2.86), hospitalization due to revascularization OR = 2.38 (1.49-3.80), hospitalization due to stroke OR = 1.72 (1.1-2.68).Compared to normotensive participants, persons with hypertension had higher prevalence of diabetes, obesity, MS, PAD, CAD, stroke, MI and AF, and more frequent need for hospitalization due to HF, exacerbation of CAD and for coronary revascularization.

Publication types

Multicenter Study

MeSH terms

Adult
Aged
Aged, 80 and over
Blood Pressure / physiology*
Cardiovascular Diseases / epidemiology*
Comorbidity
Female
Follow-Up Studies
Humans
Hypertension / epidemiology*
Male
Metabolic Syndrome / epidemiology*
Middle Aged
Poland / epidemiology
Prevalence
Retrospective Studies
Risk Assessment / methods*
Risk Factors
Young Adult