The Saga of Hydroxychloroquine and COVID-19: A Cautionary Tale
- PMID: 32673059
- PMCID: PMC7384271
- DOI: 10.7326/M20-5041
The Saga of Hydroxychloroquine and COVID-19: A Cautionary Tale
Abstract
In their article, Skipper and colleagues report the results of trial of hydroxychloroquine for patients presenting with nonsevere COVID-19. The editorialists discuss the findings and the need to examine carefully not only what we know about hydroxychloroquine and COVID-19 but also how we learned it, disseminated it, and put it into practice.
Conflict of interest statement
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References
-
- Chen Z, Hu J, Zhang Z, et al. Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial. medRxiv. Preprint posted online 10 April 2020. doi:10.1101/2020.03.22.20040758
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- National Institutes of Health. NIH halts clinical trial of hydroxychloroquine. 20 June 2020. Accessed at www.nih.gov/news-events/news-releases/nih-halts-clinical-trial-hydroxych... on 12 July 2020.
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