Rapid inactivation of SARS-CoV-2 with deep-UV LED irradiation

Emerg Microbes Infect. 2020 Dec;9(1):1744-1747. doi: 10.1080/22221751.2020.1796529.

Abstract

The spread of novel coronavirus disease 2019 (COVID-19) infections worldwide has raised concerns about the prevention and control of SARS-CoV-2. Devices that rapidly inactivate viruses can reduce the chance of infection through aerosols and contact transmission. This in vitro study demonstrated that irradiation with a deep ultraviolet light-emitting diode (DUV-LED) of 280 ± 5 nm wavelength rapidly inactivates SARS-CoV-2 obtained from a COVID-19 patient. Development of devices equipped with DUV-LED is expected to prevent virus invasion through the air and after touching contaminated objects.

Keywords: COVID-19; SARS-CoV-2; antiviral efficacy; contact transmission; deep-UV LED; fomite infection; inactivation.

Publication types

  • Letter

MeSH terms

  • Animals
  • Betacoronavirus / isolation & purification
  • Betacoronavirus / radiation effects*
  • COVID-19
  • Cell Survival
  • Chlorocebus aethiops
  • Coronavirus Infections / virology*
  • Decontamination
  • Humans
  • Pandemics
  • Pneumonia, Viral / virology*
  • SARS-CoV-2
  • Ultraviolet Rays
  • Vero Cells
  • Virus Inactivation