Impulsive and compulsive behaviors in Parkinson's disease: Impact on quality of and satisfaction with life, and caregiver burden

Aleksander H Erga; Guido Alves; Ole Bjørn Tysnes; Kenn Freddy Pedersen

doi:10.1016/j.parkreldis.2020.07.007

Impulsive and compulsive behaviors in Parkinson's disease: Impact on quality of and satisfaction with life, and caregiver burden

Parkinsonism Relat Disord. 2020 Sep;78:27-30. doi: 10.1016/j.parkreldis.2020.07.007. Epub 2020 Jul 9.

Authors

Aleksander H Erga¹, Guido Alves², Ole Bjørn Tysnes³, Kenn Freddy Pedersen⁴

Affiliations

¹ The Norwegian Centre for Movement Disorders, University of Bergen, Bergen, Norway; Institute of Biological and Medical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway. Electronic address: alkn@sus.no.
² The Norwegian Centre for Movement Disorders, University of Bergen, Bergen, Norway; Department of Neurology, Stavanger University Hospital, Stavanger, Norway; Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway.
³ Department of Neurology, Haukeland University Hospital, Bergen, Norway.
⁴ The Norwegian Centre for Movement Disorders, University of Bergen, Bergen, Norway; Department of Neurology, Stavanger University Hospital, Stavanger, Norway.

PMID: 32679528
DOI: 10.1016/j.parkreldis.2020.07.007

Abstract

Introduction: To disentangle the association between impulsive and compulsive behaviors (ICBs), health-related quality of life (HRQOL), satisfaction with life (SwL), and caregiver distress in dyads of people with Parkinson's disease (PwP) and caregivers.

Methods: Data used in this study were obtained from the ongoing Norwegian ParkWest study, a population-based longitudinal cohort study of the incidence, neurobiology and prognosis of PD in Western Norway. One hundred and one dyads of PwP free of dementia and their caregivers were included 5 years after PD diagnosis and inclusion in the ParkWest study. Standardized clinical rating scales were used to evaluate ICBs, HRQOL, SwL and caregiver distress.

Results: Of 101 PwP-caregiver dyads, self-reported ICBs were seen in 33% of PwP and only caregiver-reported ICBs in 12% of PwP. PwP-reported ICBs were associated with poorer HRQOL and SwL, whereas ICBs reported by caregivers only were associated with increased caregiver distress, but not poorer HRQOL or SwL in PwP.

Conclusions: ICBs have adverse effects on HRQOL, SwL and caregiver distress. These findings underpin the need for proper identification and management of ICBs in PwP.

Keywords: Caregiver burden; Impulse control disorders; Parkinson's disease; Quality of life; Satisfaction with life.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Caregiver Burden*
Caregivers / psychology*
Disruptive, Impulse Control, and Conduct Disorders / etiology
Disruptive, Impulse Control, and Conduct Disorders / physiopathology*
Female
Humans
Impulsive Behavior / physiology*
Longitudinal Studies
Male
Middle Aged
Norway
Parkinson Disease / complications
Parkinson Disease / physiopathology*
Parkinson Disease / psychology*
Personal Satisfaction*
Quality of Life / psychology*