Comparison of invasive and non-invasive blood pressure measurements in anesthetized female Dorset cross-bred lambs (Ovis aries)

Res Vet Sci. 2020 Oct;132:257-261. doi: 10.1016/j.rvsc.2020.07.004. Epub 2020 Jul 15.


The purpose of this study was to determine the level of agreement between invasive and noninvasive blood pressure measurements in anesthetized, non-surgically manipulated Dorset cross-bred lambs. Twelve healthy female Dorset cross-bred lambs, weighing 37.3 ± 7.4 kg (mean ± SD) underwent isoflurane anesthesia for simultaneous measurement of systolic arterial pressure (SAP), mean arterial pressure (MAP) and diastolic arterial pressure (DAP) from an invasive blood pressure source and a noninvasive oscillometric source (O-NIBP). The femoral artery was catheterized for invasive blood pressure measurements, while noninvasive blood pressure was measured from a cuff placed on the antebrachium. The Bland-Altman method was used to calculate agreement between SAP, MAP and DAP measurements. The bias ± SD between SAP, MAP and DAP measurements was 3.6 ± 12.0, 4.9 ± 9.1 mmHg and 4.1 ± 8.0, respectively. The 95% limits of agreement for SAP, MAP and DAP were - 19.9 to 27.1, -13.0 to 22.8 mmHg, and - 11.7 to 19.9, respectively. Overall, agreement was poor between femoral IBP and O-NIBP monitoring techniques in anesthetized Dorset cross-bred lambs, with O-NIBP underestimating the femoral IBP. Arterial blood pressure should be most accurately measured using an invasive blood pressure monitoring technique in lambs undergoing isoflurane anesthesia.

Keywords: Arterial blood pressure; Comparison; Noninvasive blood pressure; Sheep.

MeSH terms

  • Anesthesia / veterinary
  • Animals
  • Blood Pressure / physiology*
  • Blood Pressure Determination / veterinary
  • Blood Pressure Monitors / veterinary*
  • Female
  • Isoflurane
  • Oscillometry / veterinary
  • Sheep / physiology*


  • Isoflurane