Venous thromboembolism in people living with HIV infection (PWH)

Chiara Agrati; Valentina Mazzotta; Carmela Pinnetti; Gianluigi Biava; Michele Bibas

doi:10.1016/j.trsl.2020.07.007

Venous thromboembolism in people living with HIV infection (PWH)

Transl Res. 2021 Jan:227:89-99. doi: 10.1016/j.trsl.2020.07.007. Epub 2020 Jul 18.

Authors

Chiara Agrati¹, Valentina Mazzotta², Carmela Pinnetti², Gianluigi Biava², Michele Bibas³

Affiliations

¹ Cellular Immunology and Pharmacology Laboratory, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, Rome, Italy.
² The Clinical and Research Department, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, Rome, Italy.
³ The Clinical and Research Department, National Institute for Infectious Diseases 'Lazzaro Spallanzani'-IRCCS, Rome, Italy. Electronic address: michele.bibas@inmi.it.

PMID: 32693031
DOI: 10.1016/j.trsl.2020.07.007

Abstract

The risk of venous thromboembolism (VTE) and of recurrent VTE remain elevated in people living with HIV compared to controls still with contemporary antiretroviral therapy (ART). The pathophysiology of VTE in HIV is multi factorial and includes an interplay among traditional risk factors, HIV-specific factors, behavioral factors, exposure to ART and other therapies, coinfections, and co-morbidities.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Adult
Anti-HIV Agents / therapeutic use
Female
HIV Infections / complications*
HIV Infections / drug therapy
Humans
Male
Middle Aged
Venous Thromboembolism / complications*

Substances

Anti-HIV Agents