68Ga-Prostate-Specific Membrane Antigen-11-Avid Cardiac Metastases in a Patient With Adenoid Cystic Carcinoma, A Rare Presentation of a Rare Cancer

Clin Nucl Med. 2020 Sep;45(9):716-718. doi: 10.1097/RLU.0000000000003204.


Adenoid cystic carcinoma is a rare cancer that arises from secretory glands. Metastases are mainly seen in the lungs and bones. Cardiac metastases are extremely rare; only 1 case has previously been described. In this patient, cardiac metastases were suspected based on CT imaging. Tumor imaging by Ga-prostate-specific membrane antigen (PSMA)-11 PET is mainly used in prostate cancer patients but is also of interest in adenoid cystic carcinoma patients because of high PSMA-ligand uptake in salivary glands. Ga-PSMA-11 PET imaging supported the suspicion of cardiac metastases, because the cardiac lesions showed similar tracer uptake compared with other metastases.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Adenoid Cystic / pathology*
  • Edetic Acid / analogs & derivatives*
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Heart Neoplasms / diagnostic imaging*
  • Heart Neoplasms / secondary*
  • Humans
  • Male
  • Oligopeptides*
  • Positron Emission Tomography Computed Tomography*


  • Gallium Isotopes
  • Gallium Radioisotopes
  • Oligopeptides
  • gallium 68 PSMA-11
  • Edetic Acid