Importance of combined use of preoperative 18F-FDG PET/CT imaging and intraoperative 18F-FDG handheld gamma probe detection in recurrent papillary thyroid cancer

Hell J Nucl Med. 2020 May-Aug;23(2):201-203. doi: 10.1967/s002449912109. Epub 2020 Jul 27.

Abstract

Radio-guided surgery using an intra-operative positron emission tomography (PET) probe in recurrent thyroid cancer (RTC) can be a useful method for tumor localization, verification of complete excision and to decrease operation time. We describe a case of RTC whose serum thyroglobulin (Tg) level was 5.6ng/mL. Preoperative fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed two focal abnormalities in the anterior tracheal and right upper mediastinal regions and a handheld gamma probe was used intraoperatively to identify the hot areas seen on PET scan. Postoperative 18F-FDG PET/CT imaging after tumor excision was normal. This case shows that recurrent tumor can be localized correctly using 18F-FDG PET/CT and a surgical gamma probe.

Publication types

  • Case Reports

MeSH terms

  • Fluorodeoxyglucose F18*
  • Hand*
  • Humans
  • Intraoperative Period
  • Male
  • Middle Aged
  • Positron Emission Tomography Computed Tomography / instrumentation*
  • Preoperative Period*
  • Recurrence
  • Thyroid Cancer, Papillary / diagnostic imaging*
  • Thyroid Cancer, Papillary / surgery*

Substances

  • Fluorodeoxyglucose F18