Vaccinating in Pregnancy: Opportunities and Challenges

Prim Care. 2020 Sep;47(3):443-452. doi: 10.1016/j.pop.2020.05.001. Epub 2020 May 21.


The continuum of preconception, antenatal period, fourth trimester, and interconception period are a critical time for comprehensive care to advance maternal-child health and deliver family-centered care. Immunizations are a key component of this care delivery; however, there are intricacies around indications of vaccinations during this key period. Both active immunity to the individual receiving the vaccine as well as passive immunity passed to the fetus during pregnancy highlight the benefits of this care. Understanding the indications and benefits of vaccine administration during this continuum is critical for providers caring for individuals of reproductive age.

Keywords: Immunization; Preconception health; Pregnancy.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Maternal Health
  • Postnatal Care / organization & administration
  • Preconception Care / organization & administration*
  • Preconception Care / standards
  • Pregnancy
  • Pregnancy Complications, Infectious / prevention & control
  • Prenatal Care / psychology*
  • Prenatal Care / standards
  • Primary Health Care / organization & administration*
  • Primary Health Care / standards
  • Travel
  • Vaccines / administration & dosage*
  • Vaccines / immunology*


  • Vaccines