Components of complex movement that can be best studied using the sequence learning paradigm

J Neurophysiol. 2020 Sep 1;124(3):645-647. doi: 10.1152/jn.00769.2019. Epub 2020 Jul 29.


The sequence learning paradigm has been used extensively to study motor skill acquisition. Skilled movement involves combining smaller elements of the movement in a particular order with certain timing; in sequence learning these are typically button presses, but other motor skills may include more complex elements. This paper reviews recent evidence suggesting the sequence learning paradigm can be used to understand how the brain abstractly represents the ordering of discrete actions in a complex movement.

Keywords: cognitive; planning; prefrontal; sequence learning; submovement.

Publication types

  • Review

MeSH terms

  • Humans
  • Motor Activity / physiology*
  • Motor Skills / physiology*
  • Prefrontal Cortex / physiology*
  • Serial Learning / physiology*