Data-driven study of the COVID-19 pandemic via age-structured modelling and prediction of the health system failure in Brazil amid diverse intervention strategies

PLoS One. 2020 Jul 30;15(7):e0236310. doi: 10.1371/journal.pone.0236310. eCollection 2020.

Abstract

In this work we propose a data-driven age-structured census-based SIRD-like epidemiological model capable of forecasting the spread of COVID-19 in Brazil. We model the current scenario of closed schools and universities, social distancing of people above sixty years old and voluntary home quarantine to show that it is still not enough to protect the health system by explicitly computing the demand for hospital intensive care units. We also show that an urgent intense quarantine might be the only solution to avoid the collapse of the health system and, consequently, to minimize the quantity of deaths. On the other hand, we demonstrate that the relaxation of the already imposed control measures in the next days would be catastrophic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Betacoronavirus*
  • Brazil / epidemiology
  • COVID-19
  • Child
  • Child, Preschool
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / mortality
  • Coronavirus Infections / prevention & control*
  • Coronavirus Infections / virology
  • Disease Transmission, Infectious / prevention & control*
  • Female
  • Forecasting
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Models, Theoretical*
  • Pandemics / prevention & control*
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / mortality
  • Pneumonia, Viral / prevention & control*
  • Pneumonia, Viral / virology
  • Prognosis
  • Quarantine / methods
  • SARS-CoV-2
  • Young Adult

Grants and funding

The author(s) received no specific funding for this work.