Co-existence of cheilitis glandularis and actinic cheilitis-an update

Oral Maxillofac Surg. 2021 Mar;25(1):113-117. doi: 10.1007/s10006-020-00886-z. Epub 2020 Aug 1.


Cheilitis Glandularis (CG) is a chronic inflammatory disorder with no specific etiology that affects the minor salivary glands of the lips. The main characteristic of this condition consists of the exit of thick saliva or mucopurulent secretion through the dilated ducts present in the vermilion border of the lip, associated to varying degrees of macrocheilia. In this article we report the case of a male patient, leucoderma, 48 years old, that exhibited actinic cheilitis and glandular cheilitis. We emphasized the clinical management, diagnosis criteria and treatment, taking into consideration that GC is a rare condition and makes a differential diagnosis with other entities that may occur on lips. Although a diagnosis of CG is not difficult, its treatment is a challenge, considering the unknown etiology that hinders the development of more specific and effective treatments.

Keywords: Actinic cheilitis; Cheilitis glandularis; Oral diagnosis; Oral pathology.

MeSH terms

  • Cheilitis*
  • Humans
  • Male
  • Middle Aged
  • Salivary Glands, Minor
  • Sialadenitis*

Supplementary concepts

  • Actinic cheilitis
  • Cheilitis glandularis