Cryo-EM structure of activated bile acids receptor TGR5 in complex with stimulatory G protein

Signal Transduct Target Ther. 2020 Aug 3;5(1):142. doi: 10.1038/s41392-020-00262-z.

Geng Chen^#^{1

2}, Xiankun Wang^#^{1

2}, Yunjun Ge^#¹, Ling Ma^#^{1

2}, Qiang Chen^{1

2}, Huihui Liu^{2

3}, Yang Du¹, Richard D Ye¹, Hongli Hu⁴, Ruobing Ren⁵

¹ Kobilka Institute of Innovative Drug Discovery, School of Life and Health Sciences, The Chinese University of Hong Kong, 518172, Shenzhen, Guangdong, P.R. China.
² School of Life Sciences, University of Science and Technology of China, 230026, Anhui, P.R. China.
³ Warshel Institute for Computational Biology, The Chinese University of Hong Kong, 518172, Shenzhen, Guangdong, P.R. China.
⁴ Kobilka Institute of Innovative Drug Discovery, School of Life and Health Sciences, The Chinese University of Hong Kong, 518172, Shenzhen, Guangdong, P.R. China. honglihu@cuhk.edu.cn.
⁵ Kobilka Institute of Innovative Drug Discovery, School of Life and Health Sciences, The Chinese University of Hong Kong, 518172, Shenzhen, Guangdong, P.R. China. renruobing@cuhk.edu.cn.

^# Contributed equally.

No abstract available

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