Guidelines for human gene nomenclature

Nat Genet. 2020 Aug;52(8):754-758. doi: 10.1038/s41588-020-0669-3.


Standardized gene naming is crucial for effective communication about genes, and as genomics becomes increasingly important in healthcare, the need for a consistent language for human genes becomes ever more vital. Here we present the current HUGO Gene Nomenclature Committee (HGNC) guidelines for naming not only protein-coding but also RNA genes and pseudogenes, and outline the changes in approach and ethos that have resulted from the discoveries of the last few decades.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genes / genetics*
  • Human Genetics / standards*
  • Humans
  • Pseudogenes / genetics
  • RNA / genetics


  • RNA