Cancer Treatment and Research During the COVID-19 Pandemic: Experience of the First 6 Months

Oncol Ther. 2020 Dec;8(2):171-182. doi: 10.1007/s40487-020-00124-2. Epub 2020 Aug 4.

Abstract

The coronavirus disease-2019 (COVID-19) pandemic has had a significant impact on patients with underlying malignancy. In this article, we summarize emerging data related to patients with cancer and COVID-19. Among patients with COVID-19, a higher proportion have an underlying diagnosis of cancer than seen in the general population. Also, patients with malignancy are likely to be more vulnerable than the general population to contracting COVID-19. Mortality is significantly higher in patients with both cancer and COVID-19 compared with the overall COVID-19-positive population. The early months of the pandemic saw a decrease in cancer screening and diagnosis, as well as postponement of standard treatments, which could lead to excess deaths from cancer in the future.

Keywords: COVID-19; Cancer; Coronavirus; Immuno-oncology; Malignancy; Mortality; Pandemic; Risk; SARS-CoV-2; Therapy.