Challenges faced in the management of complicated Boerhaave syndrome: a tertiary care center experience

Pan Afr Med J. 2020 Jun 3:36:65. doi: 10.11604/pamj.2020.36.65.23666. eCollection 2020.

Abstract

Spontaneous esophageal perforation is rare and is associated with high morbidity and mortality. A spectrum of various surgical modalities ranging from primary surgical repair to esophagectomy is available for its management. The optimal management of patients presenting late in a hemodynamically stable condition is not clearly defined in the literature. A retrospective review of all patients with Boerhaave syndrome managed by a single surgical team in a tertiary care center between 2008 and 2019 was performed (n = 16). Eleven patients were initially managed in the medical intensive care unit (MICU) as non-esophageal cause and 5 patients were referred after failed management (conservative/endoscopic). Demographics, clinical presentation, characteristics of perforation, initial diagnosis, and treatment were analyzed. All patients were males with a mean age of 42.2 years. A history of ethanol use was present in 6 patients. The median delay in diagnosis and referral was 16 days (range: 11-40 days). The common presenting symptoms were chest pain (n=11), dyspnoea (n=10), vomiting (n=4) and cough (n=2). The perforation was directed into right, left, and bilateral pleural cavities in 6, 8, and 2 patients respectively. The location of perforation was distal esophagus except for one patient. One patient was successfully treated with conservative management. The remaining patients underwent esophagectomy as a definitive surgical procedure. There was no significant postoperative morbidity and mortality. Esophagectomy can be done as a one-stage definitive procedure for patients with Boerhaave syndrome who present late in a hemodynamically stable condition with acceptable morbidity and good long term outcome.

Keywords: Boerhaave syndrome; esophageal perforation; esophageal rupture; esophagectomy.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Chest Pain / epidemiology
  • Chest Pain / etiology
  • Delayed Diagnosis
  • Dyspnea / etiology
  • Esophageal Perforation / diagnosis
  • Esophageal Perforation / physiopathology
  • Esophageal Perforation / surgery*
  • Esophagectomy / methods*
  • Humans
  • Male
  • Mediastinal Diseases / diagnosis
  • Mediastinal Diseases / physiopathology
  • Mediastinal Diseases / surgery*
  • Middle Aged
  • Retrospective Studies
  • Tertiary Care Centers
  • Vomiting / epidemiology
  • Vomiting / etiology
  • Young Adult

Supplementary concepts

  • Boerhaave syndrome